Tangible cooperative gestures: Improving control and initiative in digital photo sharing

© 2015 by the authors. This paper focuses on co-present digital photo sharing on a notebook and investigates how this could be supported. While analyzing the current digital photo sharing situation we noticed that there was a high threshold for visitors to take control of the personal computer of the photo owner, resulting in inequity of participation. It was assumed that visitors would have the opportunity to interact with the notebook more freely if this threshold was lowered by distributing the user interface and creating a more public, instead of personal, interaction space. This, in turn, could make them feel more involved and in control during a session, creating a more enjoyable experience. To test these assumptions a design prototype was created that stimulates participants to use tangible artifacts for cooperative gestures, a promising direction for the future of HCI. The situation with the cooperative gestures was compared with the regular digital photo sharing situation, which makes use of a keyboard. In dyads, visitors felt more involved and in control in the design prototype cooperative gestures condition (especially during storytelling), resulting in a more enjoyable digital photo sharing experience

Introduction : analysing English syntax past and present

This book is an exploration of categories, constructions, and change in English syntax. A great many books are published on the syntax of English, both monographs and edited volumes, and yet another may seem unnecessary. However, we felt more than justified in adding to the sizeable literature here for two reasons. The first, to borrow from Richard M. Hogg and David Denison’s justification for A History of the English Language, is that ‘one of the beauties of the language is its ability to show continuous change and flexibility while in some sense remaining the same

The ethnic identity complexity of transculturally placed foster youth in the Netherlands

This study addresses the ethnic identity of transculturally placed adolescent foster youth with ethnic minority backgrounds in The Netherlands. We conducted qualitative interviews to provide insight into the lifeworlds of twenty foster youth. We found that constructing an ethnic identity was complex for these ethnic minority foster youth. The foster youth showed ethnic identity ambivalence, and contradictory messages about ethnicity by birth parents, foster parents, peers, and strangers contributed to this process. The foster youth also sometimes distanced themselves from their ethnic minority background whereby the intersection of their ethnic minority background and the background of being a foster child could play a role. Additionally, some foster youth told stories of longing for and belonging to their ethnic minority background, especially when birth parents and foster parents cooperated in ethnic socialization. Overall, contradictory and intersecting messages provided by birth parents, foster parents, and peers influenced the extent to which they experienced their ethnic identity as complex. Therefore, future studies should be conducted to provide more insight into these processes, so foster care agencies and foster parents can be trained to fulfill a more guiding role in the ethnic identity development of transculturally placed foster youth

The ethnic identity of transracially placed foster children with an ethnic minority background:A systematic literature review

BackgroundEthnic minority foster children are frequently placed in families with ethnic majority backgrounds. In the international literature these placements are most commonly called transracial placements.AimsWith this study, we aim to obtain an encompassing view of the empirical scientific literature on how transracial placements may affect the ethnic identity of foster children.Materials and methodsTo gain insight into the ethnic identity of transracially placed foster children and the way they are ethnically socialized, we conducted a systematic literature review. We thereby followed the guidelines of the PRISMA statement.ResultsTransracially placed foster children may experience higher fluctuations in their racial/ ethnic identity over time than adolescents with a minority background in the general population. They also seem to be prone to experience disconnection from, or on the contrary, connection with the birth network; and some transracially placed foster children struggle with societal messages they receive about minority ethnicity and race. They may have an increased awareness of their minority ethnic background because of different physical appearances between themselves and the foster family. Foster parents can play a pivotal role in these processes, since culturally competent foster parents may guide foster children in their ethnic identity development by being open towards children’s cultural minority background as well as being self‐reflective regarding their own cultural values and beliefs.DiscussionThe ethnic development of transracially placed foster children seems to be influenced by intersecting mechanisms of being in foster care and having a minority ethnicity. Although the selected articles assume that foster parents impact the ethnic identities of their ethnic minority foster children, none of them measured the impact of foster parents’ skills and knowledge on foster children’ s ethnic identity development directly.ConclusionBeing transracially placed impacts the ethnic identity of foster children. Foster parents need to be cultural competent to encourage their foster children’s ethnic identity development

Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase

Minor histocompatibility antigens are the main targets of donor-derived T-cells after allogeneic stem cell transplantation. Identification of these antigens and understanding their biology are a key requisite for more insight into how graft vs. leukemia effect and graft vs. host disease could be separated. We here identified four new HLA class II-restricted minor histocompatibility antigens using whole genome association scanning. For one of the new antigens, i.e., LB-PIP4K2A-1S, we measured strong T-cell recognition of the donor variant PIP4K2A-1N when pulsed as exogenous peptide, while the endogenously expressed variant in donor EBV-B cells was not recognized. We showed that lack of T-cell recognition was caused by intracellular cleavage by a protease named asparagine endopeptidase (AEP). Furthermore, microarray gene expression analysis showed that PIP4K2A and AEP are both ubiquitously expressed in a wide variety of healthy tissues, but that expression levels of AEP were lower in primary acute myeloid leukemia (AML). In line with that, we confirmed low activity of AEP in AML cells and demonstrated that HLA-DRB1*03:01 positive primary AML expressing LB-PIP4K2A-1S or its donor variant PIP4K2A-1N were both recognized by specific T-cells. In conclusion, LB-PIP4K2A-1S not only represents a novel minor histocompatibility antigen but also provides evidence that donor T-cells after allogeneic stem cell transplantation can target the autologous allelic variant as leukemia-associated antigen. Furthermore, it demonstrates that endopeptidases can play a role in cell type-specific intracellular processing and presentation of HLA class II-restricted antigens, which may be explored in future immunotherapy of AML

Trends in sexually transmitted infections in the Netherlands, combining surveillance data from general practices and sexually transmitted infection centers

<p>Abstract</p> <p>Background</p> <p>Sexually transmitted infections (STI) care in the Netherlands is primarily provided by general practitioners (GPs) and specialized STI centers. STI surveillance is based on data from STI centers, which show increasing numbers of clients. Data from a GP morbidity surveillance network were used to investigate the distribution in the provision of STI care and the usefulness of GP data in surveillance.</p> <p>Methods</p> <p>Data on STI-related episodes and STI diagnoses based on ICPC codes and, for chlamydia, prescriptions, were obtained from GP electronic medical records (EMRs) of the GP network and compared to data from STI centers from 2002 to 2007. Incidence rates were estimated for the total population in the Netherlands.</p> <p>Results</p> <p>The incidence of STI-consultations and -diagnoses increased substantially in recent years, both at GPs and STI centers. The increase in consultations was larger than the increase in diagnoses; Chlamydia incidence rose especially at STI centers. GPs were responsible for 70% of STI-related episodes and 80-85% of STI diagnoses. STI centers attract relatively younger and more often male STI-patients than GPs. Symptomatic STIs like <it>Herpes genitalis </it>and genital warts were more frequently diagnosed at GPs and chlamydia, gonorrhea and syphilis at STI centers.</p> <p>Conclusions</p> <p>GPs fulfill an important role in STI care, complementary to STI centers. Case definitions of STI could be improved, particularly by including laboratory results in EMRs. The contribution of primary care is often overlooked in STI health care. Including estimates from GP EMRs can improve the surveillance of STIs.</p